What is Southhampton like?

Travellers to the Southhampton neighbourhood in St. Louis will be sure to enjoy their stay.

How many hotels should I expect to find in the Southhampton area?

When you want to put your feet up after a day of exploring the sights in St. Louis, you can choose from 18 Expedia hotels and other accommodation options in Southhampton.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Southhampton.

What can I see and do in this St. Louis neighbourhood?

A few places to visit in the area around Southhampton include The Heavy Anchor, Das Bevo and Miniature Museum of Greater St. Louis. When you're sightseeing in St. Louis, Lindenwood Park and River des Peres Greenway Trailhead are also worth a stop.

Top 10 Southhampton Hotels of 2026

A city skyline at dusk with a prominent bridge arching over a body of water.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southhampton hotels

A swimming pool with a 40 ft depth marker, lounge chairs, and a brick wall.

1. Drury Inn & Suites St. Louis Forest Park

3.3 km from Southhampton

Tammy

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.7 km from Southhampton

Melissa

includes taxes & fees

28 Oct - 29 Oct

The Clayton Plaza Hotel sign with a stone wall and plants in front.

3. Clayton Plaza Hotel & Extended Stay

8.2 km from Southhampton

Sarah

includes taxes & fees

1 Nov - 2 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

4. The Cheshire

5.5 km from Southhampton

Matthew

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a chair, a desk, and a large window.

5. Forest Park Hotel by MDR

The Hill, 3.4 km from Southhampton

Kevan

includes taxes & fees

15 Nov - 16 Nov

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

6. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.3 km from Southhampton

MARY

includes taxes & fees

25 Oct - 26 Oct

A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

7. Aloft by Marriott St Louis Central West End

Central West End, 6.1 km from Southhampton

Brittany

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with seating, planters, and a grill.

8. Element by Marriott St. Louis Midtown

Midtown, 6.6 km from Southhampton

Julie

includes taxes & fees

25 Oct - 26 Oct

A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

9. AC Hotel St. Louis Clayton

8.1 km from Southhampton

anthony

includes taxes & fees

15 Nov - 16 Nov

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

10. AC Hotel St. Louis Central West End

Central West End, 6.6 km from Southhampton

Janice

includes taxes & fees

20 Nov - 21 Nov

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

11. Drury Plaza Hotel St. Louis Brentwood

6.9 km from Southhampton

angelia

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

12. Pear Tree Inn St. Louis Near Union Station

Downtown West, 7.9 km from Southhampton

Larry

includes taxes & fees

25 Oct - 26 Oct

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

13. Comfort Inn & Suites Saint Louis Lafayette Square

The Gate, 6.3 km from Southhampton

greg

includes taxes & fees

28 Oct - 29 Oct

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

14. SpringHill Suites St. Louis Brentwood

5.9 km from Southhampton

Aaron

includes taxes & fees

9 Nov - 10 Nov

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

15. Hotel Indigo St Louis - Central West End by IHG

Central West End, 6.5 km from Southhampton

Lydia

includes taxes & fees

25 Oct - 26 Oct

A rooftop terrace with wicker furniture, offering a city view.

16. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 9.3 km from Southhampton

Theresa

includes taxes & fees

25 Oct - 26 Oct

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

17. River City Casino & Hotel

6.7 km from Southhampton

jodi

includes taxes & fees

4 Nov - 5 Nov

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

18. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 9.5 km from Southhampton

Johnny

includes taxes & fees

30 Oct - 31 Oct

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

19. The West End

Central West End, 6.7 km from Southhampton

Trevor

includes taxes & fees

8 Nov - 9 Nov

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

20. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 6.5 km from Southhampton

Kristina

includes taxes & fees

15 Nov - 16 Nov

View all properties

Compare popular hotels in Southhampton

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Forest Park	3.0 star property	9.4 Exceptional 1,023 reviews	View
SpringHill Suites St. Louis Brentwood	3.0 star property	9.0 Wonderful 1,000 reviews	View
Home2 Suites by Hilton St. Louis/Forest Park	3.0 star property	8.6 Excellent 1,002 reviews	View
River City Casino & Hotel	4.0 star property	9.2 Wonderful 1,823 reviews	View
Drury Plaza Hotel St. Louis at the Arch	3.0 star property	9.6 Exceptional 3,809 reviews	View

Where to stay in Southhampton

Find the best Southhampton areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

See properties

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

See properties

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

See properties

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

See properties

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

See properties