What is Southhampton like?

Travellers to the Southhampton neighbourhood in St. Louis will be sure to enjoy their stay.

How many hotels should I expect to find in the Southhampton area?

When you want to put your feet up after a day of exploring the sights in St. Louis, you can choose from 18 Expedia hotels and other accommodation options in Southhampton.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Southhampton.

What can I see and do in this St. Louis neighbourhood?

A few places to visit in the area around Southhampton include The Heavy Anchor, Das Bevo and Miniature Museum of Greater St. Louis. When you're sightseeing in St. Louis, Lindenwood Park and River des Peres Greenway Trailhead are also worth a stop.

Top 10 Southhampton Hotels of 2026

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Our top choices for Southhampton hotels

1. Drury Inn & Suites St. Louis Forest Park

3.3 km from Southhampton

Jennifer

includes taxes & fees

7 Sept - 8 Sept

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.7 km from Southhampton

Greg

includes taxes & fees

9 Sept - 10 Sept

Premium bedding, pillow-top beds, desk, laptop workspace

3. Forest Park Hotel by MDR

The Hill, 3.4 km from Southhampton

wahwah

includes taxes & fees

1 Oct - 2 Oct

4. SpringHill Suites St. Louis Brentwood

5.9 km from Southhampton

Elzbieta

includes taxes & fees

27 Sept - 28 Sept

5. Courtyard by Marriott St. Louis Brentwood

6.3 km from Southhampton

Aaron

includes taxes & fees

13 Sept - 14 Sept

5 restaurants; breakfast, lunch, dinner and brunch served

6. River City Casino & Hotel

6.7 km from Southhampton

Ashley

includes taxes & fees

27 Sept - 28 Sept

7. Clayton Plaza Hotel & Extended Stay

8.2 km from Southhampton

Gail

includes taxes & fees

20 Sept - 21 Sept

8. The Cheshire

5.5 km from Southhampton

James

includes taxes & fees

13 Sept - 14 Sept

9. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.3 km from Southhampton

paullita jeanne

includes taxes & fees

6 Sept - 7 Sept

10. Aloft by Marriott St Louis Central West End

Central West End, 6.1 km from Southhampton

Changsuk

includes taxes & fees

7 Sept - 8 Sept

11. Drury Plaza Hotel St. Louis Brentwood

6.9 km from Southhampton

Eric

includes taxes & fees

13 Sept - 14 Sept

12. The Knight Center at Washington University

7.4 km from Southhampton

Nija

includes taxes & fees

20 Sept - 21 Sept

13. Comfort Inn & Suites Saint Louis Lafayette Square

The Gate, 6.3 km from Southhampton

Wolfgang

includes taxes & fees

27 Sept - 28 Sept

14. Element by Marriott St. Louis Midtown

Midtown, 6.6 km from Southhampton

Corderoa

includes taxes & fees

20 Sept - 21 Sept

15. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 9.5 km from Southhampton

TRACY

includes taxes & fees

5 Sept - 6 Sept

In-room safe, desk, blackout curtains, iron/ironing board

16. DoubleTree by Hilton St. Louis Forest Park

Central West End, 6 km from Southhampton

Kevin

includes taxes & fees

6 Sept - 7 Sept

17. Moonrise Hotel

7.7 km from Southhampton

Nicole

includes taxes & fees

7 Sept - 8 Sept

18. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 7.9 km from Southhampton

Erik

includes taxes & fees

3 Sept - 4 Sept

19. Hotel Indigo St Louis - Central West End by IHG

Central West End, 6.5 km from Southhampton

Simon

includes taxes & fees

7 Sept - 8 Sept

20. The West End

Central West End, 6.7 km from Southhampton

Isabella

includes taxes & fees

6 Sept - 7 Sept

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Where to stay in Southhampton

Find the best Southhampton areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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Top Southhampton Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Convenient downtown location for our family trip. Friendly front office personnel."

Live by Loews - St.Louis

10/10 Excellent

"First time staying at this brand. Loved this stay. In town for couple Cardinals games. Great walkable location, part of Ballpark Village, is right across street from ballpark. Super staff. Awesome indoor/outdoor bar/restaurant/lounge, plus a rooftop bar/lounge. Do have happy hr with reasonable drink prices. Hotel is newer, trendy vibe & decor. Hotel is quiet, heard no one in halls or room doors….don’t get the people who walk out their room and let door slam shut behind em. Doors are slow close which is nice. Bathrooms could use more hooks and maybe couple small shelves. Luggage carts are kept locked, need to ask for one. Def stay here again."

Hotels in Southhampton

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Our top choices for Southhampton hotels

1. Drury Inn & Suites St. Louis Forest Park

2. Hampton Inn & Suites St. Louis at Forest Park

3. Forest Park Hotel by MDR

4. SpringHill Suites St. Louis Brentwood

5. Courtyard by Marriott St. Louis Brentwood

6. River City Casino & Hotel

7. Clayton Plaza Hotel & Extended Stay

8. The Cheshire

9. Home2 Suites by Hilton St. Louis/Forest Park

10. Aloft by Marriott St Louis Central West End

11. Drury Plaza Hotel St. Louis Brentwood

12. The Knight Center at Washington University

13. Comfort Inn & Suites Saint Louis Lafayette Square

14. Element by Marriott St. Louis Midtown

15. Hyatt Regency St. Louis at The Arch

16. DoubleTree by Hilton St. Louis Forest Park

17. Moonrise Hotel

18. Fairfield Inn & Suites by Marriott St. Louis Downtown

19. Hotel Indigo St Louis - Central West End by IHG

20. The West End

Where to stay in Southhampton

Downtown St. Louis

Clayton

Central West End

Creve Coeur

St. Charles Historic District

Top Southhampton Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

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