Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Things to do
Panama City Visit an Indian town Embera and waterfall with lunch
Tour to a waterfall and Embera village with lunch included
Monkey and Sloth Jungle Habitat Panama Tour
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama Canal Wildlife Boat Safari & Panamanian Brunch
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Top hotels in Santa Ana
Casco View Apartments
The space was very nice.
Reviewed on 1 Feb, 2026
Hotel Riu Plaza Panama
We had a great stay at the RIU. Our room was spacious, clean and quiet. Our check in with Luis was great and very fast! We had great service at the main restaurant from Melissa and then again at breakfast. Mellisa was a wonderful server and she spoke very good English which is helpful to me as I ...
Reviewed on 31 Jan, 2026
Crowne Plaza Panama Airport by IHG
Clean room, acceptable dining area with good service. Pool area is great
Reviewed on 29 Jan, 2026
Waldorf Astoria Panama
Room was great, excellent view, clean and spacious.
Reviewed on 27 Jan, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Great
Reviewed on 31 Jan, 2026
Sheraton Grand Panama
Great staff
Reviewed on 15 Jan, 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.
Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.
