Santa Ana

Panama City

Plaza Santa Ana, Panama Casco Viejo
Santa Ana

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is S$171 per night from 25 Apr to 26 Apr
S$171
25 Apr - 26 Apr
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (88 reviews)
Beautiful apartments, great pool, amazing views, attentive staff, and reasonable price, just 3 blocks from Casco viejo. Whats not to like?! Marcelino was very helpful at the concierge desk, with good english, and very knowledgeable.

Reviewed on 16 Apr, 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is S$203 per night from 6 May to 7 May
S$203
6 May - 7 May
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,297 reviews)
Everything was amazing! Highly recommend stay in at RIU'

Reviewed on 17 Apr, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is S$179 per night from 12 May to 13 May
S$179
12 May - 13 May
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,518 reviews)
Room was alright. We have paid less and received more. There was an alarm for a tech room beeping all night. Can hear the people next and above us quite clearly. Lobby looks nice but room was meh. Restaurant very expensive for what you get.

Reviewed on 16 Apr, 2026

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is S$167 per night from 28 Apr to 29 Apr
S$167
28 Apr - 29 Apr
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
The hotel needs urgently a renovation. The staff is poorly trained

Reviewed on 12 Apr, 2026

Sheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is S$157 per night from 7 May to 8 May
S$157
7 May - 8 May
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,001 reviews)
Room has musky smell emanating from air-conditioning.

Reviewed on 16 Apr, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is S$79 per night from 19 Apr to 20 Apr
S$79
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,795 reviews)
I had a great stay at this property. The room was very clean and well maintained, and the air conditioning worked perfectly, which made a big difference in comfort. The staff was friendly, responsive, and always willing to help with anything we needed. Overall, everything was smooth and easy, and ...

Reviewed on 16 Apr, 2026

Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.

El Chorrillo
Calidonia

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Calidonia
Balboa

Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.

Balboa
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Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu


Santa Ana