Santa Ana
Panama City


Popular places to visit

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Cinta Costera
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.

Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.

Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Things to do

Panama City Visit an Indian town Embera and waterfall with lunch

The OG Crawl by The Panama Barcrawl - (Panama City, Panama)

From Panama City: San Blas Island Hopping Day Tour

Boat tour in the Panama Canal to Monkeys and sloths islands

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Top hotels in Santa Ana

Casco View Apartments
Beautiful apartments, great pool, amazing views, attentive staff, and reasonable price, just 3 blocks from Casco viejo. Whats not to like?! Marcelino was very helpful at the concierge desk, with good english, and very knowledgeable.
Reviewed on 16 Apr, 2026

Hotel Riu Plaza Panama
Everything was amazing! Highly recommend stay in at RIU'
Reviewed on 17 Apr, 2026

Crowne Plaza Panama Airport by IHG
Room was alright. We have paid less and received more. There was an alarm for a tech room beeping all night. Can hear the people next and above us quite clearly. Lobby looks nice but room was meh. Restaurant very expensive for what you get.
Reviewed on 16 Apr, 2026

Sheraton Grand Panama
The hotel needs urgently a renovation. The staff is poorly trained
Reviewed on 12 Apr, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Room has musky smell emanating from air-conditioning.
Reviewed on 16 Apr, 2026

Principe Hotel and Suites
I had a great stay at this property. The room was very clean and well maintained, and the air conditioning worked perfectly, which made a big difference in comfort. The staff was friendly, responsive, and always willing to help with anything we needed. Overall, everything was smooth and easy, and ...
Reviewed on 16 Apr, 2026
Other neighbourhoods around Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.

Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.

Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

