Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Cinta Costera
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Things to do
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: POIN Swing Experience
The OG Crawl by The Panama Barcrawl - (Panama City, Panama)
Boat tour in the Panama Canal to Monkeys and sloths islands
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Top hotels in Santa Ana
Casco View Apartments
Beautiful apartments, great pool, amazing views, attentive staff, and reasonable price, just 3 blocks from Casco viejo. Whats not to like?! Marcelino was very helpful at the concierge desk, with good english, and very knowledgeable.
Reviewed on 16 Apr, 2026
Hotel Riu Plaza Panama
Clean rooms
Reviewed on 17 Apr, 2026
Crowne Plaza Panama Airport by IHG
The staff were helpful and the room was clean but could use an update. The shuttle runs every hour but it would be beneficial to guests if it ran at least every 30 minutes. Just a suggestion.
Reviewed on 17 Apr, 2026
Sheraton Grand Panama
The hotel needs urgently a renovation. The staff is poorly trained
Reviewed on 12 Apr, 2026
Principe Hotel and Suites
We like Principe Hotel that is why we returned. From the check-in to the room, everything was good and we were comfortable The price is excellent for this very nice hotel. We would definitely stay there again.
Reviewed on 17 Apr, 2026
Dreams Playa Bonita Panama - All Inclusive
No activities. Food is 1/10 I left starving only ate enuff to get me by and not be sick. It’s very much so bottom of the barrel kind of resort.
Reviewed on 13 Apr, 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
