What is Santo Tomas like?

Travellers will be sure to find plenty to entertain them in Mexico City's Santo Tomas neighbourhood. Consider a visit to Hospital de Jesus Nazareno as part of your Santo Tomas travel plans.

If I need to cancel my hotel reservation in Santo Tomas, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Santo Tomas.

What is there to do around this Mexico City neighbourhood?

Hospital de Jesus Nazareno is an attraction you might want to check out while you're in Santo Tomas. While you're out sightseeing, Mexico City Arena and HDX Circus Bar are a couple of additional sights to visit in Mexico City.

Top 10 Santo Tomas Hotels of 2026

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Our top choices for Santo Tomas hotels

A modern hotel room with a blue sofa, a dining table, a separate bedroom with a bed, and a bathroom visible through an open door.

1. Holiday Inn Express Mexico Basilica by IHG

6 km from Santo Tomas

Alba

includes taxes & fees

18 Nov - 19 Nov

A multi-level outdoor patio area with seating arrangements, a round table, and potted plants.

2. Hotel Brasilia

4.2 km from Santo Tomas

sarah

includes taxes & fees

2 Nov - 3 Nov

A bar area with red and black furniture, a bar counter, and a television screen.

3. Hotel Parque Satelite

6.8 km from Santo Tomas

Yair

includes taxes & fees

2 Nov - 3 Nov

A modern indoor space with a wooden wall, a cactus, and seating area with tables and chairs.

4. KALI La Raza Mexico City

Cuauhtémoc, 4.2 km from Santo Tomas

Maria

includes taxes & fees

28 Nov - 29 Nov

A staircase leading to a building entrance with a metal railing, a green wall with plants, and a clear sky.

5. Hotel & Villas Panamá

2.6 km from Santo Tomas

Brenda

includes taxes & fees

17 Nov - 18 Nov

A modern hotel with a prominent vertical design, large windows, and a distinctive roof structure.

6. Fiesta Americana México Toreo

5.6 km from Santo Tomas

Rosa

includes taxes & fees

6 Nov - 7 Nov

A modern lobby with a red sofa, colorful chairs, a round table, and a ceiling with various words and phrases.

7. ibis Mexico Tlalnepantla

6.4 km from Santo Tomas

Gary

includes taxes & fees

8 Nov - 9 Nov

A bedroom with a bed, a ceiling fan, a large window, and a bathroom with a bathtub and a shower.

8. Hotel MX congreso CDMX, Trademark Collection by Wyndham

Venustiano Carranza, 8.5 km from Santo Tomas

Corina Marcela

includes taxes & fees

8 Nov - 9 Nov

A staircase with red railings, a red wall, and a yellow wall with a window.

9. Hotel Ancona - Adults Only

4 km from Santo Tomas

Marco Antonio

includes taxes & fees

2 Nov - 3 Nov

A modern reception area with a central counter, multiple seating options, and a high ceiling with recessed lighting.

10. Tru By Hilton Mexico City Airport

Venustiano Carranza, 11.2 km from Santo Tomas

Ruben

includes taxes & fees

10 Nov - 11 Nov

A hot tub with a cityscape view at sunset.

11. Holiday Inn Express Mexico Aeropuerto by IHG

12.5 km from Santo Tomas

Alan

includes taxes & fees

5 Nov - 6 Nov

A hotel lobby with a large yellow sign reading "HOTELES ESCALA," a black leather sofa, yellow chairs, and a glass coffee table.

12. Hotel Escala Siglo XXI

Cuauhtémoc, 9.4 km from Santo Tomas

Rebecca Abigail

includes taxes & fees

10 Nov - 11 Nov

A FIesta Inn building with a modern facade, large windows, and well-maintained landscaping.

13. Fiesta Inn Ciudad de Mexico Aeropuerto

Venustiano Carranza, 10.9 km from Santo Tomas

ALBERTO

includes taxes & fees

3 Nov - 4 Nov

A modern hotel lobby with a circular reception desk, marble flooring, and a staircase leading to upper floors.

14. WeEnjoy Hotels Aeropuerto CDMX

12.5 km from Santo Tomas

Erick

includes taxes & fees

2 Nov - 3 Nov

A modern outdoor seating area with a water feature, including a fountain and seating arrangements.

15. Courtyard Mexico City Airport

Venustiano Carranza, 11.3 km from Santo Tomas

Oscar

includes taxes & fees

24 Nov - 25 Nov

16. Camino Real Aeropuerto Mexico

Venustiano Carranza, 11.1 km from Santo Tomas

Roderick

includes taxes & fees

18 Nov - 19 Nov

An indoor swimming pool with a red wall, steps leading into the pool, and lounge chairs with umbrellas.

17. Hotel Riazor Aeropuerto

10.9 km from Santo Tomas

Marianne

includes taxes & fees

26 Nov - 27 Nov

An outdoor dining area with a table and chairs, surrounded by greenery and a modern building in the background.

18. Fiesta Americana Viaducto Aeropuerto

11.3 km from Santo Tomas

Delaney

includes taxes & fees

17 Nov - 18 Nov

A modern hotel building with a prominent sign reading "Hotel Hara".

19. Hotel Harare

Benito Juarez, 11.6 km from Santo Tomas

Adriana

includes taxes & fees

3 Nov - 4 Nov

A modern hotel room with a flat-screen TV, a desk, a comfortable sofa, and a bed with patterned bedding.

20. Econo Express Hotel by Nokte Inn

Benito Juarez, 12.3 km from Santo Tomas

Carlina Moses

includes taxes & fees

6 Nov - 7 Nov

View all properties

Compare popular hotels in Santo Tomas

Property	Property class	Guest rating
Holiday Inn Express Mexico Basilica by IHG	3.0 star property	9.4 Exceptional 1,217 reviews	View
Hotel Brasilia	3.0 star property	9.0 Wonderful 1,019 reviews	View
KALI La Raza Mexico City	2.5 star property	9.4 Exceptional 423 reviews	View
Hotel Parque Satelite	3.0 star property	9.2 Wonderful 1,312 reviews	View
Fiesta Americana México Toreo	4.0 star property	9.6 Exceptional 1,000 reviews	View

Where to stay in Santo Tomas

Find the best Santo Tomas areas for the activities you enjoy most.

An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

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A stone monument with inscriptions, surrounded by lush greenery and a clear sky.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

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A row of colorful buildings with balconies and ornate doors.

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

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A grand building with a large golden dome and classical architecture.

Historic Center

Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

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A brightly lit monument with a statue on top, surrounded by modern buildings.

Reforma

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

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Top Santo Tomas Hotel Reviews

Geneve Ciudad de México

10/10 Excellent

"excellent hotel worth the money.......very happy with the hotel."

ULIV Mexico City

10/10 Excellent

"Uliv Mexico City provided an ideal stay. The location was great for getting to all the things we wanted to see. The apartment was clean. Apartment had a kitchen equipped with basic plates and utensils, only had a fryin,g pan to cook with, but pretty sure if we had asked more would have been provided. There were plenty of good places to eat in the area, from fine dining ,to cafes and taco stands. The staff were very friendly and helpful. Would definitely stay here again."

Sevilla Palace Hotel

8/10 Good

"Nice hotel in a great location - it is a little dated, but well-maintained and classy in design. Our first night, we were very cold and discovered the heat in our room did not work, and that the bed had only a very thin blanket with no blanket in the closet. Before our second night, we asked for a blanket and were told there were none in the hotel (!). But we were very kindly provided with a space heater. Also strange that the room had a coffee maker, but no coffee. Hot tub on the roof was great."

Historico Central Hotel

10/10 Excellent

"The hotel is centrally located to many places of interest. The breakfast is simply amazing, cooked to order and they'll customize it completely for you. The free cafe is also amazing. Also a shout out to their concierge team who were more than willing to help with booking restaurants and dealing with language issues."

ULIV Pulse Roma - Condesa

10/10 Excellent

"Amazing place! The room was spotless, and all the amenities were super clean! The front desk staff was incredibly helpful and friendly. We absolutely loved staying here and will definitely be coming back! The location is perfect, with plenty of great restaurants nearby and the train station just around the corner. We 100% recommend this place! You won’t regret staying here!"

Hotels in Santo Tomas

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santo Tomas hotels

1. Holiday Inn Express Mexico Basilica by IHG

2. Hotel Brasilia

3. Hotel Parque Satelite

4. KALI La Raza Mexico City

5. Hotel & Villas Panamá

6. Fiesta Americana México Toreo

7. ibis Mexico Tlalnepantla

8. Hotel MX congreso CDMX, Trademark Collection by Wyndham

9. Hotel Ancona - Adults Only

10. Tru By Hilton Mexico City Airport

11. Holiday Inn Express Mexico Aeropuerto by IHG

12. Hotel Escala Siglo XXI

13. Fiesta Inn Ciudad de Mexico Aeropuerto

14. WeEnjoy Hotels Aeropuerto CDMX

15. Courtyard Mexico City Airport

16. Camino Real Aeropuerto Mexico

17. Hotel Riazor Aeropuerto

18. Fiesta Americana Viaducto Aeropuerto

19. Hotel Harare

20. Econo Express Hotel by Nokte Inn

Compare popular hotels in Santo Tomas

Where to stay in Santo Tomas

Roma Norte

Polanco

La Condesa

Historic Center

Reforma

Top Santo Tomas Hotel Reviews

Geneve Ciudad de México

Frequently asked questions

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