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Top Hotels with Spa in Southeast Missouri
Our top choices for Southeast Missouri hotels with a spa

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1003)
The price is S$114
includes taxes & fees
4 Sept - 5 Sept

Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (1000)
The price is S$138
includes taxes & fees
31 Aug - 1 Sept

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
8.4 out of 10, Very good, (898)
The price is S$94
includes taxes & fees
1 Sept - 2 Sept

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (739)
The price is S$159
includes taxes & fees
31 Aug - 1 Sept

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (1002)
The price is S$122
includes taxes & fees
27 Aug - 28 Aug

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1000)
The price is S$102
includes taxes & fees
24 Aug - 25 Aug

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (982)
The price is S$130
includes taxes & fees
31 Aug - 1 Sept

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very good, (669)
The price is S$82
includes taxes & fees
21 Sept - 22 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
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