Hotels in Lake Nona Medical City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lake Nona Medical City hotels

Aloft Orlando Lake Nona

Aloft Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (324 reviews)
"Our stay was great!"
United States
Kendra
The price is S$211
includes taxes & fees
6 Apr - 7 Apr
Aloft Orlando Lake Nona

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (616 reviews)
"Close to activities. Friendly staff and great breakfast buffet."
United States
Jana
The price is S$245
includes taxes & fees
3 Apr - 4 Apr
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (329 reviews)
"Great staff on front desk."
United Kingdom
David
The price is S$272
includes taxes & fees
5 Apr - 6 Apr
Residence Inn Orlando Lake Nona

Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks
3.0 star property
30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (3,053 reviews)
"This was excellent hotel. Clean and nice grounds. "
United States
Kate
The price is S$188
includes taxes & fees
25 Mar - 26 Mar
Kompose Boutique Resort at Theme Parks

Hyatt House Orlando International Drive

Hyatt House Orlando International Drive
4.0 star property
International Drive District, 20.2 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,595 reviews)
"Breakfast was excellent! Hotel is very clean. "
Canada
Danqing
The price is S$169
includes taxes & fees
22 Mar - 23 Mar
Hyatt House Orlando International Drive

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel
3.0 star property
International Drive District, 21.3 km from Lake Nona Medical City
8.6 out of 10, Excellent, (988 reviews)
"Great stay"
United States
Amanda R
The price is S$133
includes taxes & fees
1 Apr - 2 Apr
DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (1,471 reviews)
"It was great especially the breakfast "
Canada
Ahmad Taha
The price is S$136
includes taxes & fees
16 Mar - 17 Mar
La Quinta Inn & Suites by Wyndham Orlando Airport

Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,556 reviews)
"Great stay "
United States
Nancy
The price is S$152
includes taxes & fees
30 Mar - 31 Mar
Hampton Inn & Suites Orlando Airport @ Gateway Village

Hyatt Place Orlando Airport

Hyatt Place Orlando Airport
3.0 star property
Airport North, 11 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,664 reviews)
"Clean rooms, staff was very attentive, Breakfast was great! "
United States
Jeannette
The price is S$165
includes taxes & fees
1 Apr - 2 Apr
Hyatt Place Orlando Airport

Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,939 reviews)
"Clean, nice rooms , easy shuttle… perfect for what was needed!"
United States
Veronika
The price is S$176
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express Orlando International Airport by IHG

Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,087 reviews)
"Very clean, friendly staff & close to the airport easy travel "
United States
Justin Paul
The price is S$154
includes taxes & fees
6 Apr - 7 Apr
Wyndham Garden Orlando Airport

Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very good, (5,455 reviews)
"Great hotel "
United States
Aniese
The price is S$156
includes taxes & fees
6 Apr - 7 Apr
Ramada by Wyndham Suites Orlando Airport

Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1,940 reviews)
"Great hotel amazing staff "
United States
Gloria
The price is S$157
includes taxes & fees
31 Mar - 1 Apr
Cambria Hotel Orlando Airport

Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,852 reviews)
"Helpful staff, clean room, good breakfast, great location for airport travel"
United States
Lee
The price is S$167
includes taxes & fees
31 Mar - 1 Apr
Wingate by Wyndham - Orlando International Airport

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (3,012 reviews)
"Clean, great location, amazing breakfast, accommodating staff…would definitely recommend."
Canada
Kathy
The price is S$188
includes taxes & fees
5 Apr - 6 Apr
Hyatt House Orlando Airport

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
Florida Center, 21.7 km from Lake Nona Medical City
8.4 out of 10, Very good, (6,901 reviews)
"Very nice hotel"
Canada
XIAOLAN
The price is S$140
includes taxes & fees
29 Mar - 30 Mar
DoubleTree by Hilton at the Entrance to Universal Orlando

avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,185 reviews)
"Great quick stay for a good value!"
United States
Pamela
The price is S$166
includes taxes & fees
16 Mar - 17 Mar
avid hotel Orlando International Airport by IHG

Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport
2.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,824 reviews)
"Nice clean room and airport shuttle made the stay very convenient. Would defintely stay again. "
United States
Stephen
The price is S$152
includes taxes & fees
31 Mar - 1 Apr
Hampton Inn Orlando-International Airport

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,626 reviews)
"Great service and hotel!"
United States
Steven
The price is S$137
includes taxes & fees
5 Apr - 6 Apr
Rosen Shingle Creek

Holiday Inn Orlando International Airport by IHG

Holiday Inn Orlando International Airport by IHG
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
8.4 out of 10, Very good, (1,428 reviews)
"Clean room , good beds and beautiful lobby "
Canada
Linda
The price is S$169
includes taxes & fees
31 Mar - 1 Apr
Holiday Inn Orlando International Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Downtown Orlando

One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.

Explore a world of travel with Expedia