Hotels in Lake Nona Medical City
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Lake Nona Medical City hotels
9.8 out of 10, Exceptional, (273)
"Great staff and nice amenities. "
David
The price is S$201
includes taxes & fees
5 Jan - 6 Jan, 2026
9.6 out of 10, Exceptional, (594)
"Mya, at the front desk, was exceptional and was a great start to our experience!"
James
The price is S$219
includes taxes & fees
24 Dec - 25 Dec
9.6 out of 10, Exceptional, (326)
"Very clean hotel and spacious room with comfortable seating and kitchen area. The location was great for me as I was there visiting someone in an area hospital. There are also restaurants and coffee shops right outside the entrance. "
Sharon
The price is S$234
includes taxes & fees
24 Dec - 25 Dec
Kompose Boutique Resort at Theme Parks
Kompose Boutique Resort at Theme Parks30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2066)
"Very nice place to stay in, we love it!!"
Basim
The price is S$152
includes taxes & fees
24 Dec - 25 Dec
8.8 out of 10, Excellent, (3307)
"Excellent location and value, very clean and friendly check in"
Jason
The price is S$88
includes taxes & fees
4 Jan - 5 Jan, 2026
Wingate by Wyndham - Orlando International Airport
Wingate by Wyndham - Orlando International AirportAirport North, 11 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3736)
"Great accommodations and service! "
Manuel
The price is S$121
includes taxes & fees
24 Dec - 25 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Lake Nona Medical City
Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Photo by ©Disney
Open Photo by ©Disney
Bay Lake
Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.
Champions Gate
Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.
Florida Center
If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.
Downtown Orlando
One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.
Top Lake Nona Medical City Hotel Reviews
DoubleTree by Hilton Hotel Orlando at SeaWorld
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Aquatica
- Azalea Park Hotels
- Campbell Hotels
- Downtown Orlando Hotels
- Hotels near Florida Mall
- Historic Downtown Kissimmee Hotels
- Kissimmee Hotels
- Lake Hart Hotels
- Hotels with free airport shuttle in Lake Nona Medical City
- Hotels with WiFi in Lake Nona
- Luxury Hotels in Lake Nona
- Lake Nona Hotels
- Meadow Woods Hotels
- Hotels near Medieval Times
- Millenia Hotels
- Hotels near Oak Ridge Gun Range
- Oak Ridge Hotels
- Hotels near Orange County Convention Center
- Hotels near Orlando Intl.
- Hotels near Osceola Heritage Park
- Hotels near Osceola Performing Arts Center
- Hotels near Pointe Orlando
- Hotels near Silver Spurs Arena
- Southchase Hotels
- Budget Hotels in Southeast Orlando
- Universal Orlando Resort in Southeast Orlando
- Tangelo Park Hotels
- Hotels near The Ice Factory of Central Florida
- Hotels near Universal Studios Florida
- Hotels near Universal’s Volcano Bay
- Venetian Bay Villages Hotels
- Veranda Palms Hotels
- Williamsburg Hotels
- Delta Atlanta (ATL) to Orlando (MCO) flights
- Delta New York (JFK) to Orlando (MCO) flights
- Flights from Amsterdam (AMS) to Orlando (MCO)
- Flights from Manama (BAH) to Orlando (MCO)
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Boston (BOS) to Orlando (MCO)
- Flights from Buffalo (BUF) to Orlando (MCO)
- Flights from Paris (CDG) to Orlando (MCO)
- Flights from Jakarta (CGK) to Orlando (MCO)
- Flights from Cincinnati (CVG) to Orlando (MCO)
- Flights from Dallas (DAL) to Orlando (MCO)
- Flights from Washington (DCA) to Orlando (MCO)
- Flights from Doha (DOH) to Orlando (MCO)
- Flights from Dubai (DXB) to Orlando (MCO)
- Flights from Rio de Janeiro (GIG) to Orlando (MCO)
- Flights from Killeen (GRK) to Orlando (MCO)
- Flights from São Paulo (GRU) to Orlando (MCO)
- Flights from Greenville (GSP) to Orlando (MCO)
- Flights from Honolulu (HNL) to Orlando (MCO)
- Flights from Seoul (ICN) to Orlando (MCO)
- Flights from New York (JFK) to Orlando (MCO)
- Flights from Johannesburg (JNB) to Orlando (MCO)
- Flights from Karachi (KHI) to Orlando (MCO)
- Flights from Kingston (KIN) to Orlando (MCO)
- Flights from Kuala Lumpur (KUL) to Orlando (MCO)
- Flights from Kuwait City (KWI) to Orlando (MCO)
- Flights from Miami (MIA) to Orlando (MCO)
- Flights from Myrtle Beach (MYR) to Orlando (MCO)
- Flights from Oakland (OAK) to Orlando (MCO)
- Flights from Oklahoma City (OKC) to Orlando (MCO)
- Flights from Chicago (ORD) to Orlando (MCO)
- Flights from Portland (PDX) to Orlando (MCO)
- Flights from Pittsburgh (PIT) to Orlando (MCO)
- Flights from Sherman (PNX) to Orlando (MCO)
- Flights from Richmond (RIC) to Orlando (MCO)
- Flights from Rochester (RST) to Orlando (MCO)
- Flights from San Antonio (SAT) to Orlando (MCO)
- Flights from San Francisco (SFO) to Orlando (MCO)
- Flights from Singapore (SIN) to Orlando (MCO)
- Flights from San Jose (SJC) to Orlando (MCO)
- Flights from San Juan (SJU) to Orlando (MCO)
- Flights from Tallahassee (TLH) to Orlando (MCO)
- Flights from Tampa (TPA) to Orlando (MCO)
- Flights from Taos (TSM) to Orlando (MCO)
- Flights from Tucson (TUS) to Orlando (MCO)
- Flights from Concord (USA) to Orlando (MCO)
- Flights from Campinas (VCP) to Orlando (MCO)
- Flights from Montreal (YUL) to Orlando (MCO)
- Flights from Vancouver (YVR) to Orlando (MCO)
- Flights from Zürich (ZRH) to Orlando (MCO)
- Ace Rental Cars in Orlando Intl.
- Avis Rental Cars in Orlando Intl.
- Rental cars Orlando Intl. airport
- Economy Rent a Car Rental Cars in Orlando Intl.
- Europcar Rental Cars in Orlando Intl.
- Full-Size Car Hire near Orlando Intl.
- Hertz Rental Cars in Orlando Intl.
- Movida Rent A Car Rental Cars in Orlando Intl.
- Nü Car Rentals Rental Cars in Orlando Intl.
- Payless Rental Cars in Orlando Intl.
- Sixt Rental Cars in Orlando Intl.
- Thrifty Car Rental Rental Cars in Orlando Intl.