S$240 Cheap Flights from Des Moines to San Francisco

View S$240 flight on Wed, 17 Dec, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Des Moines to San Francisco (DSM-SFO)

Prices were available within the past 7 days and start at S$240 for one-way flights and S$531 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$531 Return, found 2 hours ago
S$531
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$531 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$583 Return, found 2 hours ago
S$583
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$583 found 2 hours ago
United
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$589 Return, found 2 hours ago
S$589
Return
found 2 hours ago
Select United flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$589 found 2 hours ago
United
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$636 Return, found 2 hours ago
S$636
Return
found 2 hours ago
Select United flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$636 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$641 Return, found 2 hours ago
S$641
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$641 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$647 Return, found 2 hours ago
S$647
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$647 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$654 Return, found 2 hours ago
S$654
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$654 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$667 Return, found 2 hours ago
S$667
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$667 found 2 hours ago
American Airlines
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$670 Return, found 2 hours ago
S$670
Return
found 2 hours ago
Select American Airlines flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$670 found 2 hours ago
Delta
Wed, 17 Dec - Wed, 24 Dec
DSM
Des Moines
SFO
San Francisco
S$685 Return, found 2 hours ago
S$685
Return
found 2 hours ago
Select Delta flight, departing Wed, 17 Dec from Des Moines to San Francisco, returning Wed, 24 Dec, priced at S$685 found 2 hours ago

Find the cheapest month to fly from Des Moines (DSM) to San Francisco (SFO)

November is typically the cheapest month to fly

From S$178 - S$835 per traveller.

Frequently asked questions

How much is a flight from DSM to San Francisco Intl. Airport (SFO)?
Start packing your suitcase, because round-trip flights between DSM and SFO start from S$531. That's based on airfares available within the last 7 days on Expedia for flights departing within the next year. Prices can increase quickly, so book now to get the best deal. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport (DSM) to San Francisco Intl. Airport (SFO)?
Most flights can be cancelled online, but each airline has its own set of terms and conditions. If you do need to cancel your flight, visit our Customer Service Portal and follow the instructions.
How do I find cheap flights from Des Moines Intl. Airport (DSM) to San Francisco Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport to San Francisco Intl. Airport (SFO) flights, you'll see a "no change fees" filter for you to select.
How far is the flight from DSM to San Francisco Intl. Airport (SFO)?
It's around 2,500 kilometres between Des Moines and San Francisco, so you'll be flying for a while. Keep yourself entertained by packing things like playing cards (if you're travelling with friends) or a good old-fashioned book.
Which airlines fly direct from Des Moines Intl. Airport (DSM) to San Francisco Intl. Airport (SFO)?
Currently, no airlines offer direct flights from DSM to San Francisco Airport. You'll have to book a flight with one or more stops. To score the best connections and price, lock in your airfare ahead of time.
Are DSM to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute?
It is possible to get amazing last-minute deals from DSM to SFO, but there's no guarantee. As many airlines advertise prices up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to book when you spot a bargain. Expedia compares carrier prices and updates flight deals frequently, so you can rest assured you're always seeing the latest offers.

Travel information

Origin airport
Des Moines Intl.
Destination airport
San Francisco Intl.
Return price
S$531
Distance
2474 km

Book with confidence

Perfect flights from Des Moines to San Francisco

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Experience the joy of finding cheap flights from Des Moines Intl. to San Francisco Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$240 and roundtrip prices from S$531*.
 

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*Note: Prices may vary based on availability and are subject to change.
Perfect flights from Des Moines to San Francisco

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