
Defiance Hotels from S$99
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24 Aug - 25 AugTomorrow
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28 Aug - 30 AugNext weekend
4 Sept - 6 SeptOur top choices for Defiance hotels




1. Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
David
S$151
includes taxes & fees
30 Aug - 31 Aug




2. The Wildwood Hotel
The Wildwood HotelWildwood
Hailey
S$117
includes taxes & fees
1 Sept - 2 Sept




3. Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
Josh
S$118
includes taxes & fees
13 Sept - 14 Sept




4. Comfort Inn & Suites Chesterfield - St. Louis
Comfort Inn & Suites Chesterfield - St. LouisChesterfield
Joe
S$129
includes taxes & fees
30 Aug - 31 Aug




5. TownePlace Suites by Marriott St. Louis Chesterfield
TownePlace Suites by Marriott St. Louis ChesterfieldChesterfield
Cindy
S$191
includes taxes & fees
31 Aug - 1 Sept




6. Staybridge Suites O'Fallon Chesterfield by IHG
Staybridge Suites O'Fallon Chesterfield by IHGO'Fallon
Norman
S$177
includes taxes & fees
30 Aug - 31 Aug




7. Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MOO'Fallon
Kassie
S$209
includes taxes & fees
30 Aug - 31 Aug




8. Residence Inn by Marriott O'Fallon
Residence Inn by Marriott O'FallonO'Fallon
Gerald
S$196
includes taxes & fees
13 Sept - 14 Sept




9. Hampton Inn & Suites St. Louis/Chesterfield
Hampton Inn & Suites St. Louis/ChesterfieldChesterfield
Karen E
S$162
includes taxes & fees
30 Aug - 31 Aug




10. Holiday Inn St. Louis West Six Flags by IHG
Holiday Inn St. Louis West Six Flags by IHGEureka
Rob
S$140
includes taxes & fees
21 Sept - 22 Sept




11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Holiday Inn Express & Suites St. Louis - Chesterfield by IHGChesterfield
NEBAHAT
S$168
includes taxes & fees
30 Aug - 31 Aug




12. Courtyard by Marriott St. Louis Chesterfield
Courtyard by Marriott St. Louis ChesterfieldChesterfield
Kelly
S$185
includes taxes & fees
30 Aug - 31 Aug




13. Quality Inn Near Six Flags St. Louis
Quality Inn Near Six Flags St. LouisPacific
Diane
S$137
includes taxes & fees
20 Sept - 21 Sept




14. Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
Michael Macumber
S$186
includes taxes & fees
30 Aug - 31 Aug




15. Comfort Inn Near Six Flags St. Louis
Comfort Inn Near Six Flags St. LouisPacific
David
S$136
includes taxes & fees
20 Sept - 21 Sept




16. Super 8 by Wyndham O'Fallon MO/St. Louis Area
Super 8 by Wyndham O'Fallon MO/St. Louis AreaO'Fallon
Shelly
S$99
includes taxes & fees
30 Aug - 31 Aug




17. Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
Melanie
S$161
includes taxes & fees
30 Aug - 31 Aug




18. WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
Ellen
S$130
includes taxes & fees
31 Aug - 1 Sept




19. Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
Andrea T
S$191
includes taxes & fees
30 Aug - 31 Aug




20. Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
Daniel
S$213
includes taxes & fees
30 Aug - 31 Aug
Stay near popular Defiance attractions

August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
Sugar Creek Winery
8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
Yellow Farmhouse Winery
This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
Matson Hill Park Trailhead
Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.
Broemmelsiek Park
This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
Hamburg Trail Trailhead
This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
See all hotels in Defiance
Top Defiance Hotel Reviews
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"The second room was much better and more clean that the 1st room. Breakfast was solid with biscuits & gravy, sausage & scrambled eggs. Some yogurt & fruit as well. Bagels, cream cheese. A super neat pancake maker that makes the cutest lil pancakes! Apple juice, cranberry & orange too. Coca cola products for soft drinks. Cereal & milk provided. Pool indoor & outdoor looked very clean & pristine, so did the hot tub. They were spraying down the pool deck when I was walking down to breakfast."
Sonesta ES Suites St. Louis - Chesterfield
10/10 Excellent
"Area was excellent and the employees are very friendly."
Sleep Inn & Suites O'Fallon MO - Technology Drive
8/10 Good
"Good breakfast choices. Rooms clean"
Drury Inn & Suites Southwest St. Louis
10/10 Excellent
"This is the nicest hotel I have ever stayed in. Staff were amazing. Our hotel room was SO clean. Shower was super nice. Indoor/outdoor pool was so fun! Used it every day we were there. 5:00 pm kickbacks were delicious and so convenient after being out and about all day. Breakfast was great. My children were so happy with this hotel. We cannot wait to comeback! This location was so close to Six Flags and St Louis zoo. My 6 year old is still talking about this hotel โบ๏ธ"
The Wildwood Hotel
10/10 Excellent
"The front desk staff, housekeepers and Breakfast area were stellar."
Best Western Plus Fenton
10/10 Excellent
"I found the ice cream machine to be so much a wonderful surprise! Everything was clean and everyone was quite friendly!"
Ameristar Casino Resort and Spa
10/10 Excellent
"Great location and atmosphere! Rooms are so spacious and nice. Will definitely stay again!"
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Good location to events nice shuttle worth the money room clean ."
Courtyard by Marriott St Louis Westport Plaza
10/10 Excellent
"Absolutely loved this place. Comfy beds. Spacious suites"
More cheap stays in Defiance

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
S$100
per night
26 Aug - 27 Aug

Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive O'Fallon MO
S$118
per night
13 Sept - 14 Sept
9/10 Wonderful! (1,101 reviews)

Best Western Plus St. Louis West-Westport
12220 Dorsett Rd Maryland Heights MO
S$136
per night
6 Sept - 7 Sept

Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
S$142
per night
30 Aug - 31 Aug
8/10 Very good! (1,004 reviews)

Best Western Plus Fenton
1680 Fenton Business Park Ct Fenton MO
S$145
per night
31 Aug - 1 Sept
9/10 Wonderful! (439 reviews)

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
11 Arnage Boulevard Chesterfield MO
S$168
per night
30 Aug - 31 Aug
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