What is West Second Street Historic District like?

Travellers will be sure to enjoy their time in Mesa's West Second Street Historic District neighbourhood.

How many hotels can I expect to find in the West Second Street Historic District area?

Book one of Expedia's 7 hotels and other accommodation options in West Second Street Historic District and start exploring everything Mesa has to offer.

If I need to cancel my hotel reservation in West Second Street Historic District, will I receive a refund?

Yes! Most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in West Second Street Historic District.

What are the top things to see and do in West Second Street Historic District?

Arizona Museum of Natural History, Mesa Amphitheatre and Arizona Museum for Youth are just a few of the places to visit in and around West Second Street Historic District. Nile Theater and Lo-fi Coffee are also worth a visit when you're out sightseeing in Mesa.

Top 10 West Second Street Historic District Hotels of 2026

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Our top choices for West Second Street Historic District hotels

1. Drew 251 Mesa

West Second Street Historic District

Jeanne

includes taxes & fees

4 Sept - 5 Sept

2. Drew 253 Mesa

West Second Street Historic District

includes taxes & fees

3 Oct - 4 Oct

3. The Azure Hotel

Downtown, 1.7 km from West Second Street Historic District

Betisha

includes taxes & fees

6 Sept - 7 Sept

4. Hyatt Place Phoenix/Mesa

Mesa Grande, 3.1 km from West Second Street Historic District

greg

includes taxes & fees

6 Sept - 7 Sept

5. Days Inn & Suites by Wyndham Mesa Near Phoenix

US 60 Corridor, 4.2 km from West Second Street Historic District

Gerald

includes taxes & fees

8 Sept - 9 Sept

6. City Express by Marriott Tempe

8.8 km from West Second Street Historic District

River

includes taxes & fees

6 Sept - 7 Sept

7. Hampton Inn & Suites Phoenix Tempe

9 km from West Second Street Historic District

Scott

includes taxes & fees

20 Sept - 21 Sept

8. Hampton Inn & Suites Tempe/Phoenix Airport, AZ

12.6 km from West Second Street Historic District

Brian

includes taxes & fees

7 Sept - 8 Sept

9. Holiday Inn Express & Suites Phoenix - Tempe by IHG

8.8 km from West Second Street Historic District

Suhayb

includes taxes & fees

6 Sept - 7 Sept

10. Tempe Oasis

9.1 km from West Second Street Historic District

Agus

includes taxes & fees

6 Sept - 7 Sept

11. Springhill Suites Phoenix Scottsdale Marriott

10 km from West Second Street Historic District

Marie

includes taxes & fees

7 Sept - 8 Sept

12. Element by Marriott Scottsdale at SkySong

9.8 km from West Second Street Historic District

Jose

includes taxes & fees

11 Sept - 12 Sept

13. Hyatt House Tempe/Phoenix/University

8.9 km from West Second Street Historic District

Ryan

includes taxes & fees

7 Sept - 8 Sept

Premium bedding, down duvets, in-room safe, desk

14. Hyatt Place Tempe Phoenix Airport

12 km from West Second Street Historic District

Naomi

includes taxes & fees

4 Sept - 5 Sept

15. Embassy Suites by Hilton Phoenix Tempe

9.5 km from West Second Street Historic District

Jennifer

includes taxes & fees

10 Sept - 11 Sept

Hypo-allergenic bedding, laptop workspace, iron/ironing board, free WiFi

16. Hotel Solaya, part of JdV by Hyatt

11.6 km from West Second Street Historic District

Nataly

includes taxes & fees

5 Sept - 6 Sept

17. Scottsdale Parkview Hotel

9 km from West Second Street Historic District

guillermo

includes taxes & fees

14 Sept - 15 Sept

18. GreenTree Inn & Suites Phoenix Sky Harbor

13.5 km from West Second Street Historic District

Lawrence

includes taxes & fees

6 Sept - 7 Sept

19. Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

11.6 km from West Second Street Historic District

Larry

includes taxes & fees

6 Sept - 7 Sept

Premium bedding, desk, laptop workspace, blackout curtains

20. Country Inn & Suites by Radisson, Phoenix Airport, AZ

13.6 km from West Second Street Historic District

Christian

includes taxes & fees

13 Sept - 14 Sept

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Where to stay in West Second Street Historic District

Find the best West Second Street Historic District areas for the activities you enjoy most.

A cityscape at dusk with illuminated buildings, including a Chase bank and a Sheraton hotel.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

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A sculpture of a horse in motion, surrounded by cacti and palm trees, with buildings and a street in the background.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Scottsdale Center for the Performing Arts – discover Old Town, a destination also famous for its shopping.

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A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Tom's Thumb Trail and Tonto Verde Golf Club.

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A cave with a view of palm trees and a distant cityscape.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

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A desert landscape with various cacti and sparse trees.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club are top sights worth seeing.

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Top West Second Street Historic District Hotel Reviews

Hyatt Place Phoenix / Downtown

8/10 Good

"The breakfast was not good. Everything was cold and no coffee the first day. The second day I decided to just have some fruit and a pastry for my wife but no plates . Small sample size I know but I was ask for a review so there it is. The staff was really good. Very helpful and pleasant every interaction I had with them ."