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Popular airlines to Panama
Avianca
American Airlines
United
Copa
Delta
Aeromexico
KLM
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- Book smarterSave up to 40% on select hotels after you book a flight*
Cheap round-trip flights to Panama
Prices were available within the past 7 days and start at S$459 for one-way flights and S$987 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$987 Return, found 21 hours ago
S$987
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,058 Return, found 21 hours ago
S$1,058
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,062 Return, found 21 hours ago
S$1,062
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,078 Return, found 21 hours ago
S$1,078
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,169 Return, found 21 hours ago
S$1,169
Return
found 21 hours ago

Tue, 3 Feb - Tue, 17 Feb
MAD
Madrid
PTY
Panama City
S$1,184 Return, found 1 day ago
S$1,184
Return
found 1 day ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,267 Return, found 21 hours ago
S$1,267
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,332 Return, found 21 hours ago
S$1,332
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,377 Return, found 21 hours ago
S$1,377
Return
found 21 hours ago

Fri, 25 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
S$1,427 Return, found 21 hours ago
S$1,427
Return
found 21 hours ago
Expedia offers flights to Panama to meet every traveller's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to Panama or destinations around the world and discover how easy it is to make your flight reservations on Expedia.
Panama Flights Information
Airlines serving | avianca, KLM, Air France, Iberia, EVA Airways, Turkish Airlines, American Airlines, United, Delta |
|---|---|
Roundtrip price | from S$987 |
Frequently asked questions
Top Flight Destinations In Panama
Top Flight Destinations In the World
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Top Panama Hotels
- Hotel Riu Plaza Panama
- Crowne Plaza Panama Airport by IHG
- Waldorf Astoria Panama
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- The Executive Hotel
- Hotel Riu Playa Blanca - All Inclusive
- W Panama
- Las Americas Golden Tower Panama
- Plaza Paitilla Inn Hotel
- Marriott Panama Hotel
- The Westin Playa Bonita Panama
- Hotel Ojos del Rio
- Hyatt Regency Panama City
- Dreams Playa Bonita Panama - All Inclusive
- Novotel Panama City
- Courtyard by Marriott Panama Metromall
- Ramada Plaza by Wyndham Panama Punta Pacifica
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Cars
Activities
Trending flights to Panama
These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, 1 Apr - Wed, 22 Apr
SIN
Singapore
PTY
Panama City
S$1,633 Return, found 6 days ago
S$1,633
Return
found 6 days ago
*Available to Expedia members.
