Find Luxury Hotels in Southwest Houston

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Houston Luxury Hotels

This weekend
Next weekend

Our top choices for Southwest Houston luxury hotels

The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston
5.0 star property
The Galleria
9.6 out of 10, Exceptional, (921 reviews)
"The staff is excellent and the hotel is beautiful."
United States
Stacy
The price is S$807
includes taxes & fees
15 Mar - 16 Mar
The Post Oak Hotel at Uptown Houston

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,125 reviews)
"Excellent stay!"
United States
Travis
The price is S$361
includes taxes & fees
28 Mar - 29 Mar
The Westin Houston Medical Center/Museum District

Hotel Granduca Houston

Hotel Granduca Houston
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,000 reviews)
"Everything was perfect and the renovated lobby is beautiful."
Canada
Patricia
The price is S$513
includes taxes & fees
27 Mar - 28 Mar
Hotel Granduca Houston

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,771 reviews)
"Excellent hotel and restaurant!"
United States
TIMOTHY
The price is S$306
includes taxes & fees
27 Mar - 28 Mar
Blossom Hotel Houston, Curio Collection by Hilton

JW Marriott Houston by the Galleria

JW Marriott Houston by the Galleria
4.5 star property
The Galleria
8.8 out of 10, Excellent, (1,000 reviews)
"The rooms were very clean and nice"
United States
Angela
The price is S$426
includes taxes & fees
20 Mar - 21 Mar
JW Marriott Houston by the Galleria

Houston Grand Hotel - River Oaks

Houston Grand Hotel - River Oaks
5.0 star property
The Galleria
9.2 out of 10, Wonderful, (410 reviews)
"Clean room and good service "
United States
JAIME A CHAPA
The price is S$352
includes taxes & fees
22 Mar - 23 Mar
Houston Grand Hotel - River Oaks

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
Greater Uptown
9.0 out of 10, Wonderful, (1,253 reviews)
"Clean rooms great location helpful front desk staff "
United States
Kim
The price is S$296
includes taxes & fees
1 Mar - 2 Mar
Hyatt Regency Houston/Galleria

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,000 reviews)
"Very clean room & responsive staff!"
United States
ERIC
The price is S$309
includes taxes & fees
28 Mar - 29 Mar
InterContinental Houston by IHG

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Rooms were tidy, clean and comfortable bedding. Staff extremely courteous and accommodating. "
United States
Linda
The price is S$347
includes taxes & fees
23 Mar - 24 Mar
Houston Marriott Medical Center/Museum District

Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,000 reviews)
"Lovely hotel with great location and staff!"
United States
Dalton
The price is S$354
includes taxes & fees
18 Mar - 19 Mar
Omni Houston Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.

Top Southwest Houston Hotel Reviews

Explore a world of travel with Expedia