There are several airlines that operate frequent flights from Johannesburg (JNB) to Cancun (CUN) including

• SAA with 16 flights a week
• JetBlue with 15 flights a week
• United Airlines with 11 flights a week
• Delta Air Lines with 6 flights a week
• Lufthansa Cargo with 2 flights a week

The earliest flight leaves O.R. Tambo Intl. Airport at 19:00 and arrives at Cancun Intl. Airport at 08:54. The last flight of the day departs Johannesburg at 21:30 and arrives at Cancun at 15:50.

The flight distance from Johannesburg to Cancun is about 16018 km, the shortest flight is 19 hours 59 minutes with United Airlines."

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