Top 10 San Francisco Hotels of 2026

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Property	Property class	Guest rating
Aloft by Marriott Panama	3.5 star property	8.8 Excellent 1,008 reviews	View
Plaza Paitilla Inn Hotel	3.5 star property	9.4 Exceptional 2,233 reviews	View
Courtyard by Marriott Panama Multiplaza Mall	4.0 star property	9.0 Wonderful 1,014 reviews	View
Sheraton Grand Panama	4.0 star property	8.6 Excellent 1,003 reviews	View
Decapolis Hotel Panama City	4.0 star property	8.6 Excellent 1,718 reviews	View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

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A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

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A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

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Top San Francisco Hotel Reviews

Aloft by Marriott Panama

10/10 Excellent

"Excelente ubicación y el hotel muy lindo y con excelente mantenimiento"

Central Hotel Panama Casco Viejo

8/10 Good

"Nice hotel. Great location. Good breakfast. Our only complaint is about noise. The hotel has live music in the atrium from early in the morning until about 10 pm. Our room, along with many others, had windows facing into the atrium, and the noise from the music, and sometimes large tour groups at breakfast, may disturb your sleep."

Principe Hotel and Suites

8/10 Good

"Our stay was not bad. The hotel is very appealing looking on, however new furniture or upholstery and linens are required. The obvious stains in the lounge chairs does nothing to encourage you to sit in them. This was my second visit and the skirts on the bed were in the same terrible condition, ripped and dirty. These notable conditions on my 1st visit, I thought was probably a mishap but to return a 2nd time and nothing has been done to rectify the terrible conditions, I am of the opinion that it was definitely not a mishap. We did not use the pool because it was not clean. Otherwise the stay was pleasant. The staff was nice and I appreciate the housekeeping staff for their valiant efforts"

Las Americas Golden Tower Panama

10/10 Excellent

"I had a wonderful experience at this hotel. The room was clean and comfortable, the staff was friendly and professional, and the overall service was excellent. The location was also very convenient. Everything was well maintained, and I truly enjoyed my stay. Highly recommended! I would definitely stay here again."

Courtyard by Marriott Panama Metromall

10/10 Excellent

"We stayed overnight enroute to a cruise. We were nearby Super99 grocery store, and of course metromall which had everything we needed to get before embarkation. We had the breakfast included and the kids and adults loved it. It was a great breakfast before the long journey ahead. We booked to go back after the cruise also"

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Aloft by Marriott Panama and Courtyard by Marriott Panama Multiplaza Mall.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 325 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Pacific Center. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.

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Things to do in Panama City

Hotels in San Francisco

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Our top choices for San Francisco hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

2. Courtyard by Marriott Panama Multiplaza Mall

3. Aloft by Marriott Panama

4. Plaza Paitilla Inn Hotel

5. Sheraton Grand Panama

6. Boutique Apartments Panamá Coco del Mar

7. JW Marriott Panama

8. Megapolis Hotel Panamá

9. Modern Apartments PH Living 73 SF

10. San Francisco by Wynwood House

11. Decapolis Hotel Panama City

12. Las Americas Golden Tower Panama

13. Dovle Residences by HMS-Preferred Member

14. Boutique Apartments Atlapa

15. Modern Apartments at the Hub City views

16. Residence Inn by Marriott Panama City

17. Casa Orquídea

18. Stylish Apartment With Pool Gym in Panama

19. Wanders Panama by Boutique Apartments

20. The Hub by Boutique Apartments

Compare popular hotels in San Francisco

Where to stay in San Francisco

Casco Viejo

Bella Vista

El Cangrejo

Punta Paitilla

San Felipe

Top San Francisco Hotel Reviews

Aloft by Marriott Panama

Frequently asked questions

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