Hotels in South Central Houston

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Aug - 10 Aug
Tomorrow
10 Aug - 11 Aug
Next weekend
15 Aug - 17 Aug
In two weeks
22 Aug - 24 Aug

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in South Central Houston

Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillow-top beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1738)
"Had a quick stay here and would come back again!"
The price is S$909
includes taxes & fees
19 Aug - 20 Aug
Hotel Zaza Houston Museum District
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (516)
"Nice property we are enjoying our stay. "
The price is S$253
includes taxes & fees
13 Aug - 14 Aug
La Maison in Midtown an urban B&B
Houston Marriott Medical Center/Museum District
Lobby

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Peaceful and relaxing stay."
The price is S$257
includes taxes & fees
15 Aug - 16 Aug
Houston Marriott Medical Center/Museum District
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1000)
"Highly recommended.. I will stay again."
The price is S$112
includes taxes & fees
10 Aug - 11 Aug
Americas Best Value Inn Medical Center Downtown
The Westin Houston Medical Center/Museum District
Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Always great stay"
The price is S$219
includes taxes & fees
10 Aug - 11 Aug
The Westin Houston Medical Center/Museum District
Hilton Houston Plaza/Medical Center
Sun deck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very good, (1504)
"Nice hotel and perfectly located "
The price is S$140
includes taxes & fees
5 Sept - 6 Sept
Hilton Houston Plaza/Medical Center
Wanderstay Boutique Hotel
1 bedroom, in-room safe, individually decorated, individually furnished

Wanderstay Boutique Hotel

2.0 star property
10.0 out of 10, Exceptional, (41)
"Great stay!"
The price is S$182
includes taxes & fees
17 Aug - 18 Aug
Wanderstay Boutique Hotel
Newly Built Modern 3 Bedroom Houston Home
Internet

Newly Built Modern 3 Bedroom Houston Home

2.0 star property
10.0 out of 10, Exceptional, (1)
Newly Built Modern 3 Bedroom Houston Home
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.4 out of 10, Exceptional, (1001)
"Great clean property, pleasant atmosphere. "
The price is S$221
includes taxes & fees
24 Aug - 25 Aug
InterContinental Houston by IHG
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very good, (408)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is S$173
includes taxes & fees
17 Aug - 18 Aug
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hilton University of Houston
1 bedroom, premium bedding, down duvets, pillow-top beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (849)
"Perfect for new students and families."
The price is S$234
includes taxes & fees
5 Sept - 6 Sept
Hilton University of Houston
Spacious Houston 3bed3 Bath Family Townhome
Internet

Spacious Houston 3bed3 Bath Family Townhome

2.0 star property
8.0 out of 10, Very good, (1)
"The property was clean and new it was nice. Top Terrace in the downtown view was breathtaking they do have a elevator but there was no access to it we had to climb 4 floors. the garage door opener was not working also the garage door close and open on its own after a couple of minutes they put only one face towel and one napkin for bathroom if there is a two people per bedroom they should at least provide Two Face towels and two napkins. In the master bathroom there was only one small rug in...
The price is S$474
includes taxes & fees
14 Aug - 15 Aug
Spacious Houston 3bed3 Bath Family Townhome
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is S$322
includes taxes & fees
20 Aug - 21 Aug
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Modern Cozy Home with King Bed
Private kitchen

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is S$447
includes taxes & fees
18 Aug - 19 Aug
Modern Cozy Home with King Bed
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Private kitchen

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is S$744
includes taxes & fees
17 Aug - 18 Aug
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
The price is S$897
includes taxes & fees
14 Aug - 15 Aug
Posh Dtwn Midtown Home w Stunning Roof-topterrace
The Green Haus Luxxe Cabana Rooftop Retreat
Desk, Internet

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The price is S$880
includes taxes & fees
1 Sept - 2 Sept
The Green Haus Luxxe Cabana Rooftop Retreat
The Oasis Checkmate HTX Rooftop
Desk, soundproofing, iron/ironing board

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
The Oasis Checkmate HTX Rooftop
Southmore Boulevard Motel
Premium bedding, blackout curtains, free WiFi

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (217)
"Good area"
The price is S$98
includes taxes & fees
14 Aug - 15 Aug
Southmore Boulevard Motel
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1003)
"Very clean and peaceful place to stay close to the hospital 🏥 "
The price is S$124
includes taxes & fees
22 Aug - 23 Aug
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green showing a square or plaza, a city and a skyscraper
Downtown Houston map

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center map

Texas Medical Center

2 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Heights map

Houston Heights

You'll enjoy the coffee shops and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.

Houston showing a city and a skyscraper
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Central Houston Hotel Reviews

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

10/10 Excellent
"The place was very clean and you could walk around parts of the city nearby, like if theres a concert at warehouse live it’s less than 10 minutes walking. The hosts were very nice and communicated early enough to make plans, asking if we wanted a fresh breakfast or continental, room cleanings, how to get in if they were not there. They were awesome!"
Austin 2-night trip
Posted 2 days ago
La Maison in Midtown an urban B&B

Frequently asked questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other top choices in the neighbourhood include La Maison in Midtown an urban B&B and MyCrib Houston Hostel.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1143 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape and Cullen Sculpture Garden. Houston Zoo and Continental Club are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.